Search Result "Pyruvate Kinase M2 (PKM2)"


Pyruvate Kinase M2: Regulatory Circuits and Potential for Therapeutic Intervention

Journal: Current Pharmaceutical Design
Volume: 20 Issue: 1 Year: 2014 Page: 2595-2606
Author(s): Vibhor Gupta, Kathryn E. Wellen, Sybille Mazurek, Rameshwar N. K. Bamezai

Mini-Review Article

Roadmap to Pyruvate Kinase M2 Modulation - A ComputationalChronicle

Journal: Current Drug Targets
Volume: 24 Issue: 6 Year: 2023 Page: 464-483
Author(s): Deep Rohan Chatterjee,Moumita Ghosh Chowdhury

Research Article

Synthesis of a Sulfonamide Pyruvate Kinase M2 Activator for Cancer Therapy

Journal: Current Organic Synthesis
Volume: 14 Issue: 4 Year: 2017 Page: 578-581
Author(s): Qun-Zheng Zhang,Dian Zhang,Fei Huang,Cong-Yu Ke,Qing Pan,Xun-Li Zhang

Research Article

Rationalization of the activity Profile of Pyruvate Kinase Isozyme M2 (PKM2) Inhibitors using 3D QSAR

Journal: Current Topics in Medicinal Chemistry
Volume: 21 Issue: 0 Year: 2021 Page: 1-14
Author(s): Merugumala Kusuma,Sahil Arora,Sourav Kalra,Anuhar Chaturvedi,Michael Heuser,Raj Kumar

General Review Article

Recent Advances on PKM2 Inhibitors and Activators in CancerApplications

Journal: Current Medicinal Chemistry
Volume: 31 Issue: 20 Year: 2024 Page: 2955-2973
Author(s):

Research Article

Integrated In Silico-In Vitro Discovery of Lung Cancer-related Tumor Pyruvate Kinase M2 (PKM2) Inhibitors

Journal: Medicinal Chemistry
Volume: 12 Issue: 7 Year: 2016 Page: 613-620
Author(s): Xiangyun Ye, Yinjia Sun, Yunhua Xu, Zhiwei Chen, Shun Lu

Research Article

Diallyl Disulfide Inhibits Breast Cancer Stem Cell Progression and Glucose Metabolism by Targeting CD44/PKM2/AMPK Signaling

Journal: Current Cancer Drug Targets
Volume: 18 Issue: 6 Year: 2018 Page: 592-599
Author(s): Xinhua Xie,Xiaojia Huang,Hailin Tang,Feng Ye,Lu Yang,Xiaofang Guo,Zhi Tian,Xiaofang Xie,Cheng Peng,Xiaoming Xie

Review Article open access plus

Inhibition of Glycolysis and Glutaminolysis: An Emerging Drug Discovery Approach to Combat Cancer

Journal: Current Topics in Medicinal Chemistry
Volume: 18 Issue: 6 Year: 2018 Page: 494-504
Author(s): Nicholas S. Akins,Tanner C. Nielson,Hoang V. Le

Review Article

Phytometabolites Targeting the Warburg Effect in Cancer Cells: A Mechanistic Review

Journal: Current Drug Targets
Volume: 18 Issue: 9 Year: 2017 Page: 1086-1094
Author(s): Mohadeseh Hasanpourghadi, Chung Yeng Looi, Ashok Kumar Pandurangan, Gautam Sethi, Won Fen Wong, Mohd Rais Mustafa

Review Article

Targeting Kinase Interaction Networks: A New Paradigm in PPI Based Design of Kinase Inhibitors

Journal: Current Topics in Medicinal Chemistry
Volume: 19 Issue: 6 Year: 2019 Page: 467-485
Author(s): Pranitha Jenardhanan,Manivel Panneerselvam,Premendu P. Mathur

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